RAF Typhoon jets have conducted a mission with France's air force in a coordinated attack targeting an hidden munitions depot in Syrian territory employed by the IS group, according to the UK's MoD.
The facility, identified by reconnaissance, was assessed as storing arms and explosives, the statement said, and was positioned in mountainous terrain just to the north of the ancient city of Palmyra in central Syria.
"Our fighter planes utilized Paveway IV guided bombs to target a several access tunnels providing entry to the facility... initial indications suggest the strike was effective," the MoD said.
There was no evidence of any civilian impact in the attack on Saturday evening and each participating jet returned to base without incident, the MoD added.
The Typhoon FGR4s were assisted by a Voyager tanker plane.
The Islamic State group - referred to as the so-called Islamic State - enforced extremist governance over parts of both Syria and Iraq prior to its 2019 collapse.
"This strike shows British leadership, and determination to operate in unison with allied nations, to stamp out any resurgence of Daesh and their dangerous and violent ideologies in the region," Britain's Defence Chief the minister stated.
British military aircraft have carried out surveillance missions over Syrian airspace to "forestall any attempted comeback" of IS subsequent to its military defeat at the battle of Baghuz in 2019, the ministry said.
"I must thank all the members of the UK armed forces who took part in this operation for their professionalism and their bravery," Healey commented. "Including them were numerous British troops deployed over the festive period. This operation, to eliminate terrorist threats who threaten our security, demonstrates how UK forces are always on standby, continuously, protecting the UK domestically and strong abroad."
In December, the United States armed forces carried out what it called a "large-scale strike" against Daesh sites in the country, subsequent to an assault resulted in the deaths of two US servicemembers and a local interpreter in the Palmyra area.
The U.N. says Daesh still has an estimated 5,000 to 7,000 militants in Iraq and Syria.